Could the remarkable DNA-protecting proteins of tardigrades change the future of humanity in space!? The day mRNA and radiation therapy will transform

Could the remarkable DNA-protecting proteins of tardigrades change the future of humanity in space!? The day mRNA and radiation therapy will transform

The protein Dsup from the world's toughest organism, the tardigrade, acts as a "molecular shield" by closely associating with DNA to protect it from radicals and radiation. In foundational research from 2019, nucleosome binding was demonstrated, and by 2025, it was reported that temporary expression in mouse tissues using mRNA could reduce radiation damage. Its applications are broad, spanning medicine (reducing side effects of radiation therapy), space (countermeasures against cosmic rays), and agriculture (crop resistance). However, undesirable effects have been reported depending on cell types and expression conditions, making safety and targeting crucial future considerations. On social media, expectations and caution are in a delicate balance.